SnapGene 8.1.1 was released on June 18; 2025.$$$Fixes$$$Added SpyTag; SpyCatcher; and EV linker features to the common features database$$$Address various issues with duplicating files$$$Remove activation controls from the Contact Information dialog$$$Improved stability when printing$$$Fixed an issue that could delay or prevent quitting$$$Fixed issues with moving files to and from the Trash if the open project is hosted on iCloud$$$Addressed issues with printing to PDF on macOS$$$Eliminate circular / linear buttons from the top right of Map view when viewing Protein sequences which are never circular$$$Fixed an issue where some menus were shown partially off screen$$$Fix intensity of the 1000 bp band in the FroggaBio 1 Kb Plus Ladder$$$Fix various issues on Windows such as the file and folder panel becoming unresponsive after opening files by double clicking them on the Desktop or in Windows Explorer.

SnapGene 8.1.0$$$May 20; 2025$$$SnapGene 8.1 updates Enzymes view to provide a streamlined UI consistent with other table views; includes numerous improvements to navigating files and data management; extends multi-file operations to any open file as well as Project search results; and adds a number of new coloring options that provide for enhanced visualization of your data.$$$$$$Streamlined Interfaces Easily identify key information with streamlined expandable rows in the refreshed Enzymes view which provides enhanced filtering options and more intuitive scrolling. Controls in the Secondary Structure view now float above the content and the structure list and statistics have been modernized.$$$$$$Improved Search Results and Actions$$$$$$Live search results update when files are added; renamed; modified or deleted; while improved selection behavior; filtering; and sorting options allow you to more easily identify and modify files.$$$$$$Adding a Touch of Color$$$$$$A number of new coloring options allow you to visualize residues and their associated chemical and transmembrane properties; locate buttons in the side toolbar; and switch between light and dark modes.$$$$$$Navigation and Data Management$$$$$$Efficiently navigate; annotate and manage your plasmids via the streamlined files and folders panel; which now enables viewing and performing bulk annotation and file transformations on all open sequence files. Focus on Region to zoom into larger sequences.$$$$$$For more details refer - https://www.snapgene.com/updates/snapgene-version-8-1-0

SnapGene 8.1.0$$$May 20; 2025$$$SnapGene 8.1 updates Enzymes view to provide a streamlined UI consistent with other table views; includes numerous improvements to navigating files and data management; extends multi-file operations to any open file as well as Project search results; and adds a number of new coloring options that provide for enhanced visualization of your data.$$$$$$Streamlined Interfaces Easily identify key information with streamlined expandable rows in the refreshed Enzymes view which provides enhanced filtering options and more intuitive scrolling. Controls in the Secondary Structure view now float above the content and the structure list and statistics have been modernized.$$$$$$Improved Search Results and Actions$$$$$$Live search results update when files are added; renamed; modified or deleted; while improved selection behavior; filtering; and sorting options allow you to more easily identify and modify files.$$$$$$Adding a Touch of Color$$$$$$A number of new coloring options allow you to visualize residues and their associated chemical and transmembrane properties; locate buttons in the side toolbar; and switch between light and dark modes.$$$$$$Navigation and Data Management$$$$$$Efficiently navigate; annotate and manage your plasmids via the streamlined files and folders panel; which now enables viewing and performing bulk annotation and file transformations on all open sequence files. Focus on Region to zoom into larger sequences.$$$$$$For more details refer - https://www.snapgene.com/updates/snapgene-version-8-1-0

SnapGene 8.0.3 was released on March 26; 2025.$$$$$$Fixes$$$Restore missing option to print the Info panel$$$Fixed an issue that prevented showing the full list of features and primers after toggling off zoom mode$$$Fixed an issue that could prevent finding some primer binding sites or matches for searches that wrap around the numerical origin$$$Fixed an issue where double clicking a File or otherwise attempting to start SnapGene a second time would eventually require activating again$$$Fixed opening some .apr VectorNTI alignment files$$$Updated various libraries (libemf; pcre2; zlib; Minizip; OpenSSL; xz) to the latest versions

SnapGene 8.0.2 was released on January 22; 2025.$$$$$$Detailed Changes$$$Added a Prefer Smaller UI option on Windows to adjust how the interface is scaled$$$Improved the look and feel of buttons$$$Improved Japanese and Chinese translations$$$Fixes$$$Fixed file associations on Ubuntu$$$Improved stability when searching$$$Fixed contextual menu actions for file search results$$$Fixed an issue where in some situations sequences were not positioned correctly when aligning to a reference sequence$$$Fixed the Uncheck all Primers command and the Full Descriptions checkbox in the import primers dialog$$$Fixed various issues where after performing a file search the previously selected file was shown instead of search results$$$Fixed issues with deleting trimmed regions and inserting into trimmed regions when viewing an alignment to a reference$$$Fixed an issue where the mini map in sequence view could disappear when toggling off alignments$$$Fixed various issues that often resulted in the full set of history colors not being shown in History view or when printing history.$$$Fixed an issue where not all Features or Primers were shown after clearing the filter

SnapGene 8.0.1 was released on November 20; 2024.$$$$$$Detailed Changes$$$Added MW Markers from Applied Biological Materials$$$Various textual enhancements$$$Added keyboard shortcut for Zoom$$$Fixes$$$Fixed various issues when moving unsaved files$$$Fixed issues with storing and resurrecting ancestral sequences$$$Fixed circularizing a single sequence$$$Improved stability when editing annotations in Features and Primers views$$$Show features/primers column header in lower pane when splitting the view$$$Ensure when splitting the view both copies of Features or Primers views sort annotations and are filtered the same way$$$Fixed issues with inverting selected annotations in Features and Primers views$$$Fixed issues with inserting bases at the beginning of an aligned sequence$$$Fixed various issues where qualifiers could be cut off in features view if they were long and need to wrap to fit in the window; have multiple lines of text; or a larger font size was used$$$Improved display of CviJI? on Windows$$$Fixed an issue where No Matches was shown in Features or Primers view when no Features or Primers exist$$$Improved placement of No Matches message$$$Fixed an issue where the Golden Gate Cloning dialog would appear to never finish when in fact a cloning strategy was not possible because amplification of the insert to add Golden Gate sites results in activating one or more Golden Gate sites that previously were near the sequence ends but not flanked with enough bases to result in a cleavage site$$$Fixed an issue where circularizing; linearizing; changing the topology; Make Protein; Add Primers; Import Features; and various other actions were being performed on a prior file and folder selection instead of the visible document$$$Corrected link to User Guide link about Primers$$$Updated feature label placement options to not be checked if feature labels are toggled off which allows you to select a placement and show labels with one click.$$$Ensure quick actions are not shown if no files are selected in the file and folder panel$$$Fixed various issues with user based licenses$$$Fixed an issue where selecting Primers in Primers view did not properly update the sequence selection or allow you to copy Primers$$$Fixed the Ctrl+E shortcut for Choose Enzymes on Windows$$$Restored Date Added and Visibility to Primers views Sort By dialog$$$Restored Visibility to Features views Sort By dialog$$$Fixed issues with copying and pasting Primers into Microsoft Word$$$Fixed an issue where the filter controls would fail to find matches in Features and Primers views if an annotation was not expanded$$$Restored ability to manually install a license

SnapGene 8.0.0 was released on November 05; 2024.$$$$$$Overview$$$SnapGene 8.0 brings a fresh look and feel to the main data viewers; with new capabilities for bulk annotation and data manipulation; and new ways to edit alignments to a reference sequence.$$$$$$Bulk annotate your plasmids with features and primers$$$Quickly detect common features and add primers from a list onto multiple sequences selected in the Project folder panel; change sequence attributes like methylation and topology and easily perform alignments and gel simulations on selected sequences.$$$$$$$$$Modern; streamlined Map; Sequence; Features and Primers views$$$Refreshed Map; Sequence; Features and Primers views are restructured and simplified to highlight key data and capabilities; with flexible filtering and sorting added to Features and Primers tables.$$$$$$$$$$$$$$$Edit Alignments to a Reference DNA Sequence$$$You can now validate your sequences with confidence by editing the gap positions in your Sanger traces and virtual constructs when using Align to a Reference DNA Sequence.$$$$$$Enhancements to File and Folder Interactions$$$Data management is streamlined with improved file selection in the folder panel and new visualization and manipulation of unsaved files.$$$$$$$$$Detailed Changes$$$Enhanced annotating and converting multiple files in Projects$$$Import features or detect common features in multiple DNA files$$$Import primers from a list or SnapGene; VNTI or Clone Manager files onto multiple sequences$$$Circularize; linearize; or flip multiple nucleotide files$$$Change file attributes of multiple sequences including methylation; topology; and strandedness $$$Choose enzymes to be shown for multiple DNA files $$$Edit DNA or RNA ends for multiple sequences$$$Make DNA; RNA; or Protein for multiple sequences$$$Trim history in multiple files$$$Enhanced file management capabilities in Projects$$$Added ability to select folders and added indication of partial folder selections$$$Quickly clear the entire selection or deselect files by type$$$Deselect files for other types by Opt/Alt clicking the X right of the file count for a given file type$$$The file / folder selection is now cleared when closing the last tab in the project window$$$Added help link$$$Improved visualization and manipulation of unsaved changes$$$A yellow dot is shown next to files in the folder panel and in the tab$$$An alert is shown at the top of the project folder tree$$$Added options to Save All; Discard All or Select Unsaved Files in the project$$$Modernized Map and Sequence Views$$$Moved tabs to the top and the selection bar to the bottom$$$Move sequence view minimap to bottom of the view$$$Moved the chosen enzyme set indicator to the selection bar$$$Replaced the Zoom button at the bottom left (which can still be accessed view the View menu) with a Find button to toggle the search controls and added support to search while viewing a ssRNA or ssDNA structure$$$Replaced the “Description Panel” checkbox at the bottom with an “Info” button at the top$$$Replaced the “Language” button at the top left with a “Settings” button$$$Streamlined the side toolbar by moving less commonly used actions to side menus and/or a new Display button at the top right. Consistent predictable icons now shown regardless of view option settings$$$Updated the look and feel of controls at the top right of history view and the message that is shown if no history is present$$$Added a green checkmark icon at the top right to indicate if a sequence is “Confirmed Experimentally”$$$Updated; added; and modernized many tooltips which now show without a delay$$$Modernized and now dismissable alerts have been moved from the top to the bottom right$$$Alerts for content (such as enzymes; features; or primers) that could not be shown now include a link to a comprehensive list and information on what the user can do to see more of the desired content$$$Modernized Features and Primers views$$$Modern look and feel$$$Allow expanding and collapsing individual features and primers$$$M